Table of Contents
This article has been a long time coming. As a long-time resident of Prague, I know many areas well, and that local insight makes researching Prague hotels a whole lot easier.
Since I aim to cover everything useful about the Czech capital here on my blog, a guide to where to stay in Prague simply had to be part of it.
Back in my student days, I bounced between dorms and apartments, which gave me a solid feel for different Prague neighborhoods. That experience, plus tips from friends and acquaintances, helped shape this list.
Think of this as my general guide to Prague hotel recommendations based on personal experience and local research. I also suggest seasonal picks in my other Prague posts. There are just so many hotels in Prague that it makes sense to offer tailored options.
Quick note on naming: I use the local neighborhood names. Prague is divided into both neighborhoods and numbered municipal districts (like Prague 1, Prague 2, etc.). These often overlap and can be confusing, so I’ve stuck with what locals actually use and added the numbered info as well for your convenience.
I start with the neighborhoods most interesting for visitors and work outward to more local areas. That said, I don’t cover every single corner of the city. There’s really no reason to stay way out on the edge.
Also, this guide doesn’t cover the airport. Prague Airport has just one on-site hotel. You can read my review of it here.
Enough said, let’s get to it! For each neighborhood, you’ll get a short intro and three Prague hotel options: one luxury, one mid-range, and one budget-friendly pick.
Old Town (Staré Město) – Prague 1
Staré Město, or the Old Town, is Prague’s historic core and the tourist center of the city. It’s an ideal place to stay for first-time visitors, especially if you’ve only got a few days in the Czech capital. The top sights are clustered close together here, so you can cover a lot in a short amount of time. Plus, hotels in Prague Old Town are plentiful.
At the heart of it all is Old Town Square, surrounded by winding medieval lanes and beautiful old buildings. You’ll find major landmarks right on the square: Prague’s Astronomical Clock (the third oldest in the world), the soaring Old Town Hall tower with the ornate Municipal House, as well as the Klementinum Library just to name a few.
That convenience comes at a cost, though. You’ll be sharing the area with plenty of other visitors, so expect heavy crowds, especially in high season. Prices for hotels, food, and drinks also tend to be higher here.
And if you’re someone who values authenticity over tourist hotspots, this part of Prague might feel a little too staged or overrun. I’m just trying to set your expectations straight here!
Luxury: Four Seasons Prague
Great for luxury seekers and castle views
Four Seasons Hotel Prague has long been the city’s gold standard for luxury, at least until recently (hint: check the Josefov section for the new contender).
Set right on the Vltava River at the edge of Old Town, it still delivers everything you’d expect from the Four Seasons name: flawless service, timeless style, and top-tier comfort. All located in 4 interconnected buildings.
The most exclusive suite even comes with a direct, unobstructed view of Prague Castle. A rare treat!
Mid-Range: Allure Hotel Prague
Great for couples who want peace near the action
Allure Hotel is a refined four-star stay on the quieter side of Old Town, right near the border with the Josefov quarter. That means you’re still within walking distance of all the major sights, but just far enough from the chaos to breathe.
The rooms are a stylish blend of modern and classic, with soft color palettes and thoughtful touches. There’s a charming courtyard terrace, a cozy bar and restaurant, and a buffet breakfast to start your day off right.
Additionally, right in front is one of Prague’s most iconic bars—La Casa Blů. It doubles as a laid-back Mexican restaurant during the day and was even featured in the cult Czech film The Loners (Samotáři).
If you want comfort and elegance in a central but peaceful spot, Allure is a solid pick.
Budget: The RoadHouse Prague
Great for solo travelers and social vibes
The RoadHouse isn’t just a place to crash, it’s one of the city’s original hostels and still one of the best.
Tucked into a quiet street near Charles Bridge, it offers a social, laid-back vibe without the party hostel chaos.
The dorms are clean and comfy with privacy curtains, and the staff go out of their way to make everyone feel at home.
If you’re traveling solo or on a budget but still want style, warmth, and a sense of community, this is the spot.
Jewish Quarter (Josefov) – Prague 1
Josefov, Prague’s Jewish Quarter, is the city’s smallest neighborhood and often gets lumped in with the Old Town. But it has a distinct character of its own.
This compact area is where you’ll find most of Prague’s Jewish heritage sites, including the Old Jewish Cemetery and several synagogues.
It borders the Old Town Square, so you’re never far from the action, but it feels a little calmer and perhaps even more refined.
If you stay here, expect elegant architecture, luxury boutiques, and a quieter atmosphere, with layers of history in nearly every corner.
Luxury: Fairmont Golden Prague
Great for design lovers and high-end luxury
If you’re after the very best, Fairmont Golden Prague is it. Fresh off a massive top-to-bottom reconstruction and reopened in June 2025, this five-star hotel brings serious wow factor to the edge of Old Town. It sits right at the end of Pařížská Street, Prague’s most upscale boulevard, and delivers stunning views over the city’s spires and rooftops.
Formerly the InterContinental, it’s been completely transformed—think sleek modern luxury meets rich local history and curated Czech art. There are six restaurants and bars to choose from, including a rooftop spot that makes the most of those killer views.
The Fairmont brand was chosen by Czech millionaires who poured billions into the reconstruction, mostly out of philanthropy, to represent the hotel’s new high standard.
I used to come here to hit the gym back in its InterContinental days (a welcomed job perk!) and once even got to one of its legendary weekend brunches. That was way, way back in the day. :)
Mid-Range: The Emerald
Great for boutique hotel fans and art lovers
The Emerald blends boutique charm with apartment-style comfort in the heart of Josefov. Housed in a beautifully restored historic building, it offers a mix of uniquely designed studios and suites, some with dreamy bathtubs right in the room. The location is prime: just steps from Old Town Square and within easy reach of all the Jewish Quarter landmarks.
It’s a mid-range stay, though prices reflect the prestige of the neighborhood, so expect to pay a bit more than you would elsewhere in Prague.
Also in the same building, you’ll find U Pivrnce, a restaurant serving authentic Czech food. It’s where I usually take my foreign friends. The walls are covered in illustrations by Petr Urban, one of the top Czech cartoonists known for his signature humor.
Budget: Hostel Franz Kafka
Great for budget travelers who want central convenience
Hostel Franz Kafka is a small, no-frills hostel in an absolutely unbeatable location, just steps from Old Town Square. The rooms are basic but clean, and it’s not just for backpackers. Private rooms are available too, making it a decent budget option even for couples or solo travelers looking for privacy.
Just a heads-up: avoid anyone offering currency exchange on the street in this area, as they’re often running scams.
Lesser Quarter (Malá Strana) – Prague 1
Malá Strana – meaning “Lesser Town” or “Little Quarter” – is the area across the Vltava River from the Old Town, lying mainly under the gaze of Prague Castle. But don’t let the name fool you.
Connected to the center of the city via the 14th-century Charles Bridge, Malá Strana is one of the most historical quarters of the city and was home to nobles and their palaces for centuries.
The backdrop of this old part of the city – featuring spires that erupt from terracotta roofs, elegant Baroque architecture, and a network of narrow lanes – makes for a romantic space to explore.
Sights here include the stunning Baroque Church of Saint Nicholas, the Petřín Lookout Tower with its Eiffel Tower vibes, and the grand Wallenstein Palace complete with beautifully landscaped gardens that are open to the public.
Staying in this corner of the city is ideal for anybody who likes losing themselves among elegant architecture and enjoying carefree walks. It’s a particularly attractive area in the summer months, when terrace cafes and bars come alive with customers along the riverside area.
Parts of it can get quite hilly, though, especially further away from the river. Malá Strana is full of cobblestones, too.
Luxury: Augustine Hotel
Great for history buffs and quiet luxury
The Augustine is a five-star gem tucked into a quiet corner of Malá Strana—a former 13th-century monastery turned luxury hotel, complete with tranquil cloistered gardens and vaulted hallways.
It’s part of Marriott’s Luxury Collection, but it still feels deeply local, especially thanks to its in-house St. Thomas brewery, which continues the monks’ centuries-old brewing tradition. I once won a dinner there in the historic cellar brewery and it was fantastic.
The hotel’s location between Prague Castle and Charles Bridge means you’re close to everything, yet just far enough to escape the tourist crowds.
Mid-Range: Hotel U Zeleného hroznu (At the Green Grape)
Great for romantic stays with a historic twist
This boutique-style hotel boasts a perfect location for sightseers. Situated just 500 meters away from Prague Castle, it’s also easy to walk to Charles Bridge and the Old Town Square beyond from here. It’s located on a small hill called Jánský vršek, so just be prepared to walk up.
Rooms feature original 17th-century beams, arches, and frescoes. The old-world charm continues in the outdoor courtyard area, where guests can enjoy breakfast during the summer months.
Budget: Hotel U 3 Pštrosů (By 3 Ostriches)
Great for unbeatable Charles Bridge access while on budget
Situated inside a 16th-century Renaissance property, this compact hotel features a collection of 18 rooms for guests to choose from. Each has been decorated with tasteful historic details, including antique furniture; one room even boasts original Renaissance painted wooden ceilings.
The hotel’s restaurant is a cozy option for an evening meal, serving up a selection of international and Czech cuisine, while there’s also a delicious breakfast included in the room rate.
The most unique feature of this hotel—aside from the name, which means “Three Ostriches”—is its location right by Charles Bridge. You simply can’t stay any closer.
Hradčany (The Castle District) – Prague 1
Hradčany is where Prague shows off its royal side! This is the Castle District, home to the entire Prague Castle complex, the fairytale-like Nový Svět (New World), and the gorgeous Strahov Monastery and Library,which, in my opinion, rivals the better-known Klementinum.
While it’s full of history and sweeping views, don’t expect a ton of cafés or shops, amenities are limited. Aside from the castle crowds, the neighborhood is surprisingly quiet and peaceful. If you want a stay with charm, history, and space to breathe, this hilltop enclave is hard to beat.
Luxury: Hotel Hoffmeister
Great for spa lovers and peaceful castle proximity
Even though it’s technically located in Malá Strana, Hotel Hoffmeister & Spa sits right on the border with Hradčany, making it the only five-star option in Prague’s Castle District.
Tucked away on a quiet street just beneath Castle Hill, it’s the kind of place where even celebrities stay when they want privacy and easy access to the city’s most historic sights.
The hotel combines classic elegance with a full-service spa carved into the hillside, and the location means you’re only a short (20-minute) walk from Prague Castle while still avoiding the crowds.
Mid-Range: Romantik Hotel U Raka
Great for charm seekers and romantic escapes
Romantik Hotel U Raka is a truly special place, and while it sits at the higher end of mid-range, the charm is well worth it. Set in a beautifully preserved wooden building, it’s tucked into Nový Svět (New World),one of the most charming and peaceful corners of Hradčany.
The hotel feels like a countryside escape right in the middle of Prague. Back when I worked at a travel startup, we had some bloggers stay here and they were completely blown away. I’ve only seen the garden and the lobby myself, but I was just as impressed.
Budget: Questenberg Hotel
Great for scenic views and budget elegance
Hotel Questenberg may not be super cheap, but it’s as budget-friendly as it gets in Prague’s Castle District. Housed in a former Baroque monastery right next to Strahov Monastery, it offers a peaceful, historic setting with sweeping views over the city.
Rooms are cozy and classic, with wooden beams and period details that give it real character. The location is hard to beat—you’re just a short walk from Prague Castle, yet far enough from the tourist crowds to feel tucked away.
New Town (Nové Město) – Prague 1, Prague 2
The New Town of Prague is only relatively new – it was still established in 1348, making it just a few centuries younger than the Old Town. This is actually the largest of the official five towns which comprised Prague, and was established by Charles IV – aka Wenceslas, the first King of Bohemia to be crowned Holy Roman Emperor.
There are a handful of medieval buildings dating back to the New Town’s establishment, but many of the churches and buildings of this area are Gothic and Baroque. The area is centered around Wenceslas Square (more like a boulevard than a square), which was once a horse market.
Staying in Nové Město is a good option for those who want to visit Prague’s cultural attractions. It’s here that you’ll find the National Museum, which showcases the history of Czechia through a variety of cultural, historical, and scientific items and exhibits.
There’s also Prague City Museum (set to reopen in fall 2025 after a massive renovation), which focuses more on the history of the city itself, the fun National Film Museum, featuring interactive displays, and the Museum of Communism, to name a few.
In terms of accommodation, there’s a range of just about everything here – from modern holiday rentals all the way to high-end boutique hotels.
Luxury: W Prague Hotel
Great for design lovers and modern luxury
W Prague, part of the Marriott portfolio, brings bold, modern luxury to one of Prague’s most iconic buildings—the freshly restored Grand Hotel Evropa, a masterpiece of Art Nouveau architecture right on Wenceslas Square. The renovation was done with care, blending historical details with W’s signature edgy design.
There’s a standout restaurant on the ground floor and sleek, design-forward rooms upstairs.
A colleague of mine recently visited, even peeked into the corridors, and was amazed by the beautifully renovated, grand interiors.
Just a heads-up: Wenceslas Square is currently undergoing a long-term tram line reconstruction, expected to finish in 2027. So while the location is central, there may be some slight noise and disruption outside.
Mid-Range: Almanac x Alcron Prague
Great for art deco fans and foodies
Almanac Hotel, formerly known as Alcron, is a true staple on the city’s hotel scene—a classic that blends Art Deco elegance with modern comfort. Step into the grand lobby and you’d never guess the rooms are priced this reasonably.
It’s just a stone’s throw from Wenceslas Square, making it a great base for exploring the center.
The hotel’s restaurant held a Michelin star until 2017; there’s a different chef now, and time will tell if the star returns.
I often stop by Elias Coffee Shop, the cozy café tucked into the ground floor. It’s a quiet gem!
Budget: Sophie’s Hostel
Great for stylish budget stays
Sophie’s Hostel is a design-forward budget stay in a solid location—close enough to walk to the center, but placed in a quieter part of town. The rooms, both dorms and privates, are surprisingly beautiful for the price, with a modern, boutique feel you don’t usually find at this level.
Only the private rooms have A/C, so that’s something to keep in mind if you’re visiting in summer.
Friends of mine stayed here and couldn’t stop talking about the breakfast, it’s worth adding on.
Vinohrady – Prague 2, Prague 10
The residential neighborhood of Vinohrady was, once upon a time, a vineyard-covered area dating back to the 14th century. Today, it’s a polished part of Prague filled with cool cafés, leafy streets, microbreweries, and stylish gastropubs.
The stretch between I.P. Pavlova and Jiřího z Poděbrad (JZP) Square is especially known as Prague’s hipster zone, with artisan coffee, design shops, and indie vibes.
One of the local favorites is Havlíček Gardens, or Havlíčkovy sady, better known as Grébovka. This Renaissance-style park has it all: vineyards, cafés, fountains, a manmade grotto, and lovely city views.
Riegrovy Sady is another local go-to, especially for sunset views over Prague Castle and relaxed afternoons in the beer garden.
Just a short walk away, Náměstí Míru serves as the heart of Vinohrady, anchored by the majestic Basilica of St. Ludmila and known for hosting cozy Easter and Christmas markets.
It has a local feel but an open-minded atmosphere, attracting a mix of expats and curious travelers who blend right in with the neighborhood crowd. That’s why many consider it the best area to stay in Prague.
By day, this laid-back corner of Prague offers a welcome break from the tourist scene, with parks full of families and friends soaking up the sun. It’s very tourist-friendly—most places offer English-speaking service.
I’ve lived here for over five years. It’s become more cosmopolitan, and while English is widely spoken, it still holds on to its original vibe. Just a tip: if you’re after brunch on a weekend, definitely make a reservation.
Vinohrady borders Prague’s New Town and has superb connections to the historical city center. Whether you hop on the metro, tram, or even a bus, getting around is effortless. When I rented a place there, real estate agents still referred to it as the city center—and honestly, it feels like it.
Luxury: Le Palais Art Hotel
Great for art lovers and wellness-focused travelers
Le Palais Hotel is a true luxury standout in the Vinohrady district—a five-star retreat housed in a beautifully restored Belle Époque villa.
This boutique hotel blends old-world elegance with curated contemporary art, and many of the rooms feature balconies, marble bathrooms, and views over the city’s rooftops.
There’s also a small wellness center with a sauna and massage treatments, perfect after a day of exploring.
It’s hidden in a quiet, leafy part of Vinohrady, just a short walk from trendy cafés and wine bars.
Mi-Range: Ametyst Hotel Praha
Great for families and boutique comfort
This hotel may be large, but it offers plenty in terms of boutique style. For one thing, there are so many different types of room sizes to opt for – all the way up to family suites – that you’ll find something to suit your style.
Rooms feature ambient lighting, wood floors, modern furniture, and sparkling bathrooms. Days here start with a hearty breakfast, which is included in the price of the room, while there’s also a selection of bars, eateries and cafés to sample in the local neighborhood.
I lived just around the corner from this hotel and can swear it’s a great location in Vinohrady.
Budget: Czech Inn
Great for budget travelers and hostel-style charm
Czech Inn is one of Prague’s most well-loved budget stays. It’s set in a stunning 19th-century building I’ve been photographing for decades.
It blends boutique design with hostel affordability, offering everything from stylish dorms to sleek private rooms.
The vibe has always been great here—there’s usually a small crowd hanging out in front, giving it a social, welcoming energy without feeling chaotic.
Inside, you’ll find modern interiors, a cozy café, and a lively basement bar.
It’s a solid base in Vinohrady with easy tram access to the center.
Tram no. 22 stops right in front!
Vršovice – Prague 10
Vršovice has a lot to live up to. Like several of Prague’s former industrial and working-class neighborhoods, it’s completely reinvented itself and is now a bastion of cool.
Lonely Planet once called it “Prague’s most happening hangout,” and the New York Times listed Krymská Street as one of the best in Europe. I even wrote about it in Lonely Planet’s book Secret City.
Thankfully, the hype is justified. Vršovice captures what “Bohemian” really means. Not just another gentrified neighborhood, but a place where authentic, everyday life blends effortlessly with laid-back creative hubs, stylish eateries, and a raw, lived-in charm.
While Krymská Street gets most of the attention, I also love the vibe around Vršovické náměstí—there’s a great mix of local spots to eat, drink, and just hang out.
Vršovice is also home to two of Prague’s beloved football clubs: SK Slavia Prague and Bohemians 1905.
It’s a fully residential neighborhood, so you won’t find luxury hotels here but that’s part of the charm.
Mid-Range: Iris Hotel Eden
Great for drivers and football fans
Iris Hotel Eden is a comfortable, mid-range pick located in a more residential part of Vršovice. While it’s not in the trendiest pocket of the neighborhood, it makes up for it with practical perks—like plentiful (free!) parking and a tram stop just steps away, making it easy to get into the city center.
The hotel sits next to a football stadium, with a shopping mall just across the road, giving you easy access to stores, cafés, and casual dining.
Budget: Family Lorenz & Coffee House
Great for coffee lovers and cozy vibes
This welcoming, rustic-style accommodation option in Vršovice provides guest house style lodgings that’s perfect for a budget traveler in Prague.
The onsite cafe serves up high-quality coffee and selection of meals, while there’s also an enchanting terrace and garden to relax in.
The location is great: there’s a tram stop just outside, meaning you can be in the center of the city in no time.
Žižkov – Prague 3
If you’re after a hipster enclave in Prague, take note of Žižkov. This once working-class district has kept its gritty edge but grown into a creative, youthful hub.
It’s still a little rough around the edges, but that’s part of the charm. You’ll find students, artists, and expats rubbing shoulders in dive bars, indie cafés, and live music venues. A lot of the neighborhood’s energy revolves around the University of Economics, where I studied myself.
Žižkov sits just behind the main train station, making it super accessible, but it feels like a world apart from the polished Old Town. It’s not just nightlife and subculture here, though. You’ll also find historic landmarks like the Žižkov TV Tower, Prague’s boldest example of Communist-era architecture, and Vítkov Hill, with its dramatic city views and the National Memorial.
Žižkov is a great choice if you want to stay somewhere with character, local flavor, and a bit of edge, without straying too far from the city center.
Luxury: Courtyard by Marriott Prague City
Great for business travelers and convenience
Part of the international Marriott hotel chain, this large hotel comes complete with all the amenities you’d expect from this well-known brand. There’s a bar and restaurant, a fitness center and a number of shared spaces to relax in.
Set in a big, modern building, the hotel features a prime location, with Flora metro stop and a shopping center directly accessible from the hotel itself. Parukářka park is near there too.
Mid-Range: Theatrino Hotel
Great for architecture buffs and stylish stays
Theatrino Hotel, as the name suggests, is set inside a former Art Nouveau theatre. Here you can enjoy the ambience of this former theater, which retains its early 20th-century charm but has been lovingly updated for the modern day.
The main theater hall has been turned into an eatery and event space, while guest rooms are traditional, but still stylish and spacious. Amenities abound, and include a bar, sauna and good transport links on the doorstep with a tram stop just a block away.
Budget: Gregory House
Great for value stays with local feel
Set within an apartment block turned ho(s)tel, Gregory House features a wide selection of room sizes to suit different types of travelers. There’s everything from a double room all the way to an apartment with its own terrace and kitchen to choose between.
This place offers great value for money, with nice, clean rooms that feature modern decor, as well a top location just a 15-minute walk from Prague Central Station. A bus stop is a block away and a tram stop only two. It’s perfect for all budget travelers.
My friend lived in this street and can confirm it’s a good location.
Holešovice – Prague 7
Holešovice feels like the industrial cousin of Žižkov’s student scene, a neighborhood of former warehouses and factories now repurposed into creative spaces, restaurants, galleries, and bars. Just a 10-minute tram ride from the city center, it’s the kind of place where contemporary culture meets gritty charm.
Be sure to check out Vnitroblock, a creative hub that combines a café with galleries, boutiques, and a cool industrial vibe.
Another must in the neighborhood is the DOX Centre for Contemporary Art, known for its thought-provoking exhibitions and striking architecture.
Holešovice isn’t built around a single main square—it has a few smaller centers that each offer something different. Strossmayerovo náměstí, with its striking church, is always lively. Ortenovo náměstí is another good area to explore, more like a park, with a more laid-back local feel.
The neighborhood is also known for its green spaces. Letná Park offers sweeping views over the city, tree-lined walking paths, and a popular beer garden that comes alive in warmer months. Right next door is Stromovka Park, one of Prague’s largest, once a royal hunting ground and now a favorite among joggers, skaters, and picnic-goers.
The neighborhood also hosts the Exhibition Grounds, which bring extra foot traffic to the area near Stromovka during major events, but it rarely feels overcrowded. Holešovice is a great pick for travelers who want to stay somewhere artsy, spacious, and a little off the beaten path.
Luxury: Mama Shelter
Great for creative types and trendy comfort
Mama Shelter Prague is the most luxurious option you’ll find in Holešovice, even if it doesn’t carry the official 5-star label.
From the outside, it may look a bit boxy, but step inside and you’ll find playful, design-forward interiors that feel anything but ordinary.
I once attended an event there and loved the vibe, and a friend who stayed at the hotel couldn’t stop raving about it.
There’s a tram stop right out front with direct connections to the city center, and you’ll find plenty of great spots to eat in the area, too.
Mid-Range: Absolutum Wellness Hotel Prague
Great for spa lovers and peaceful nights
Featuring namesake spa treatments, saunas, plunge pools, and hot tubs, Absolutum Wellness Hotel is the place to stay if you feel like really pampering yourself.
The relaxing vibe carries through to the guest rooms, which are filled with natural light and feature earthy materials like thick wood and exposed brick.
The on-site restaurant serves a hunger-inducing menu and makes a great spot for an evening drink.
Funny enough, I discovered it by accident while having lunch with a friend, and couldn’t believe I hadn’t known about it before. The reason? The hotel sits on a quiet side street, even though it’s right next to the Holešovice train and metro station (plus a tram stop), which I pass through each time I go to the office. :)
It’s also on the way to the zoo, ranked the 5th best in the world, located in Prague’s Troja district, just across the river from Holešovice.
Budget: Kings Residence Prague
Great for charm on a budget
This three-star hotel is nestled in a historic property with period features to match, making it a charming place to stay despite being affordable for budget travelers.
Located down a quiet neighborhood street, you’ll still find plenty of bars and cafes in the vicinity. Plus, it’s just a 30 second walk to the nearest tram stop.
Karlín – Prague 8
Karlín has a similar trajectory to Žižkov and Holešovice—once a gritty, overlooked part of Prague, it’s now one of the city’s most revitalized neighborhoods. The devastating floods of 2002 ended up triggering a complete transformation, breathing new life into the area’s pastel-colored Art Nouveau buildings, leafy pedestrian zones, and a growing number of creative businesses.
Today, Karlín is one of Prague’s top foodie destinations. Nearly every corner has a café, bistro, or restaurant that balances delicious menus with stylish design. It’s the kind of place where even a casual lunch spot feels thoughtfully curated.
One of the best-known hangouts here is Kasárna Karlín, a former army barracks turned cultural hub with everything from art exhibitions and open-air film screenings to volleyball courts and coffee stands. It perfectly captures the neighborhood’s creative energy.
I worked in Karlín for a few years, and the place really got under my skin. It’s easy to fall for its everyday charm.
All the recommended hotels listed here sit near Florenc, the transit-heavy edge of Karlín that borders Prague’s Old Town. That means you’ll have easy access to both the heart of the city and Karlín’s own lively, laid-back streets.
Luxury: Hilton Prague
Great for business travelers and skyline views
Hilton Prague is the only true 5-star hotel in Karlín, and it definitely makes an impression. It’s a huge property, and when you walk into the vast, light-filled lobby, it feels almost like stepping into a giant greenhouse.
The rooms are arranged along the outer walls, leaving the central atrium open and airy, which adds to the hotel’s spacious feel. The location is excellent, with easy access to the city center and riverfront paths.
A friend of mine used to work there and always spoke highly of the service. And if you’re into cocktails with a view, Cloud 9 Sky Bar on the upper floor is well worth a visit.
Mid-Range: Botanique Hotel Prague
Great for design lovers and green vibes
This modern, design-focused hotel takes its inspiration from nature. Recently renovated, all 214 rooms at Botanique Hotel feature large, comfortable beds, organic amenities, and bright, light interiors for a relaxing stay.
The shared guest spaces are equally stylish and include a bar and bistro, which serves up signature cocktails and considered cuisine; there’s also a modern gym to make full use of.
As a bonus, public transport is just on the doorstep—it’s right at Florenc with metro / tram / bus connections.
I’ve been hearing only praise about this hotel from travelers and went to check its interior. It’s beautifully green, perfectly representing the name.
You seriously can’t go wrong with this pick.
Budget: B&B Hotel Prague City
Great for simple stays near transit
Newly opened in 2013, this contemporary hotel features bright, modern rooms at budget-friendly prices.
Conveniently located for those who don’t mind hopping on a tram or metro to Prague’s top sights and central transport hubs, the hotel also features a buffet breakfast to start the day.
There’s also plenty of (paid) parking, in case you’re on a road trip or feel like hiring a car.
I used to work nearby and have a soft spot for the area—especially that big, beautiful church at the center of it all.
Dejvice – Prague 6
Dejvice is one of Prague’s most dignified residential neighborhoods, home to embassies, university buildings, and grand Communist-era architecture.
It was once a quiet rural area but became a favored address for Prague’s elite, including the top brass of the former Czechoslovak Communist Party. You can still spot traces of that era, especially at the monumental Grand Hotel International, a prime example of Socialist Realist architecture modeled after Moscow’s “wedding cake” towers.
Despite the imposing buildings, Dejvice feels leafy and peaceful. It’s full of wide boulevards, quiet parks, and some truly great cafés and restaurants.
Dejvice’s Vítězné náměstí is also a transport hub, with Metro line A running straight through and a direct bus route to the airport. You can be at Wenceslas Square in ten minutes, yet the area feels worlds away from the tourist bustle.
If you like spacious hotels, a more suburban vibe, and excellent connectivity without the crowds, Dejvice delivers. It’s also right next to Ořechovka, a gorgeous villa-lined district that looks more English countryside than Prague. Technically it’s part of neighboring Střešovice, but it blends right into Dejvice’s calm, elegant vibe.
Luxury: Vienna House Diplomat Prague (Wyndham)
Great for airport access and comfort
This giant of a modern hotel is a comfortable and well-appointed property to spend a few nights in Prague.
Guests can settle into stylish monochrome rooms with leather seating areas, large beds, and sleek, well-designed bathrooms.
The hotel comes with top amenities which include a much-loved sushi restaurant, Katsura, a fitness center and a bar. Location-wise, transport on the doorstep allows you to be in the center of Prague within minutes.
Mid-Range: Grand Hotel International Prague
Great for retro charm and leafy calm
The famous Communist-era Grand Hotel International remains in top-notch condition.
This sprawling property has several different rooms for guests to book; while they’re not overly modern or luxurious, they’re still classically classy.
There’s also several different facilities for guests to make full use of, including a cocktail bar, a fitness center and a cafe and restaurant.
Budget: Hotel Meda of Museum Kampa
Great for metro access and simple stays
This easygoing accommodation option features traditionally decorated rooms – unfussy, but clean and comfortable.
Situated along a quiet street just outside the offcial Dejvice perimeter, Hotel Meda is close to a metro station, which puts you just two stops from the Old Town.
It’s a great option for budget travelers as it also includes breakfast in the price.
Smíchov – Prague 5
Smíchov is a neighborhood of contrasts—commercial and lively at its core, but hiding leafy escapes just a short walk away. Most of the action centers around Anděl, a major metro and tram hub surrounded by offices, cinemas, and the massive Nový Smíchov shopping mall.
It’s buzzing during the day, and even more so in the evenings when crowds gather around bars, restaurants, and the local multiplex.
That said, the area does attract a few characters after dark—people who might be struggling or on the fringes of society. I spent a summer renting here and never felt unsafe, but it’s the kind of place where staying aware is smart.
Smíchov isn’t just about Anděl, though. The neighborhood stretches south toward Sacre Coeur Park, a peaceful hillside retreat tucked behind a former convent, and east toward Zahrada Kinských, a gorgeous, sloping park that merges with Petřín Hill. These green spaces make it easy to escape the buzz and enjoy a more laid-back side of the district.
Luxury: Mamaison Hotel
Great for riverside romance and quiet charm
Mamaison Riverside Hotel brings classic elegance to the Smíchov riverfront, with a stunning Art Nouveau façade and views of the Vltava.
This boutique hotel sits just across the bridge from the National Theatre, placing you within walking distance of both Prague’s historic center and the leafy corners of Smíchov.
Inside, the vibe is refined and romantic, with high ceilings, rich fabrics, and polished wood floors. It’s the most luxurious option in this part of town, offering a quieter stay without sacrificing easy access to the city’s highlights.
Mid-Range: Andel’s by Vienna House (Wyndham)
Great for modern comfort and shopping access
Andel’s Prague is a stylish, reliable mid-range option right in the heart of modern Smíchov.
It’s located just steps from the Anděl metro and tram hub, making it convenient for getting around the city.
The rooms are spacious and sleek, with a design that leans more business-chic than cozy, but still comfortable.
You’ll also have a huge shopping mall, a cinema, and plenty of restaurants right at your doorstep.
It’s a solid choice if you want comfort, good service, and easy access to both local life and the historic center.
Budget: Hotel Augustus et Otto
Great for affordable stays with character
Situated inside a renovated 19th-century building, this hotel combines period features with modern amenities for an ideal place to stay for a couple of days in the city.
Guest rooms here are cozy, featuring large windows, high ceilings and wood floors.
Staff are particularly friendly and will help you with sightseeing tips, while the location is also great – within walking to the city center but well connected by public transport.
There’s also secure private parking in case you need it.
Nusle – Prague 2, Prague 4
Tucked beneath Vyšehrad and stretching along the southern edge of Vinohrady, Nusle is one of those neighborhoods most tourists never set foot in or pass through without ever knowing its name.
But for travelers who don’t need postcard views out the window, Nusle offers an authentic slice of Prague life with solid tram connections, a relaxed pace, and just enough going on to make it comfortable.
There’s not much in the way of tourist infrastructure, but you’ll still find everything you need: grocery stores, bakeries, cozy cafés, local pubs, and family-run restaurants. It’s residential to the core. I once lived in a tiny apartment right on the border with Vinohrady, and I loved that little hideout.
It’s also surprisingly well connected. Several tram lines and the Vyšehrad metro station make getting around easy. And if you do want a bit of greenery, Vyšehrad park is just up the hill—a dramatic, historic spot with wide views over the river.
If you’re the kind of traveler who doesn’t need the action right outside your door, Nusle is a solid, affordable base with local charm and no pretensions.
Luxury: Grand Hotel Prague Towers
Great for budget-friendly luxury and city views
Grand Hotel Prague Towers is the only five-star option in the Nusle neighborhood, and it’s been a local landmark for years. I lived nearby one summer, back when it was still called Corinthia, and always admired its sleek silhouette, wondering where the entrance was (it’s hidden below street level).
The location is super convenient, right next to the Vyšehrad metro station, which gets you into the center in just a few minutes.
I once had a fancy dinner there with friends, and everything (from the service to the views) was spot-on.
Inside, you’ll find modern, well-equipped rooms with panoramic city views, a wellness floor with a pool, and several dining options. It’s a true five-star experience, but at a surprisingly reasonable price.
Mid-Range: Union Hotel
Great for vintage charm and quick tram access
Hotel Union is a solid mid-range choice in Nusle, housed in a historic building just steps from a tram stop.
I used to live just two tram stops away and would often spot the hotel from the tram window, always curious about what it looked like inside.
Well, the reviews are pretty positive, and the photos definitely deliver on charm. Inside, you’ll find traditionally styled rooms with high ceilings, warm tones, and all the basics for a comfortable stay. The hotel also offers a restaurant and wellness services, including a small sauna.
It’s in a great location with quick tram access to the city center. You’ll be in the heart of Prague within 20 minutes.
Budget: Penzion Palouček
Great for no-frills comfort and local convenience
Penzion Palouček is a simple, no-frills option set in a residential building. It’s ideal if you’re after clean, budget-friendly accommodation without the extras.
My cousin used to live on the same street, so I know the area well. There’s a tram stop just around the corner, and you can be in the city center in minutes. It’s a practical base if you’re more interested in exploring Prague than splurging on where you sleep.
I hope this guide gave you a clearer idea of where to stay in Prague, and maybe even helped you find the perfect hotel. I’ve poured countless hours into researching the best Prague hotels, writing, and drawing from my own local experience to make sure it’s genuinely useful.
If you end up staying at one of my recommended spots, I’d love to hear how it went. I plan to update this guide regularly to keep it accurate, fresh, and full of real, honest insights.
Safe travels and enjoy your time in our beautiful Czech capital!